A tension-filled operating room is a recurring scene in the drama "Obstetrics and Gynecologists" whose original Japanese title is "GYNE," (pronounced gi-nay and shorthand for obstetrics and gynecology). There, heroine Nachi Hiiragi (Norika Fujiwara) barks orders and saves lives. She also earns the wrath of her colleagues, and on occasion her patients, for her intolerance toward anyone who disagrees with her principle of being concerned only about saving the lives of newborns and the strong-armed tactics she employs to get her way.

Japan's OB/GYN profession currently faces an acute shortage of doctors, and the harsh working conditions exposed in "GYNE" show why. Doctors are called in at all hours and work on 30 plus hour shifts. High risk procedures must be performed amid threats of malpractice suits. The tensions never subside.

Apart from giving out medical instructions, the beautiful and competent Hiiragi remains virtually silent in the first episode, presenting a stubborn and complex character whose eccentricity torments Satoshi Tamaki (Yusuke Kamiji), the young intern assigned to her. Surrounding the unlikely pair is an equally colorful cast of characters ranging from an inaccessible senior professor, his attractive lawyer, the kind-hearted chief doctor and the department director who clumsily tries to mediate disputes. As the story unfolds, the traumatic truth behind Nachi's radical actions is revealed.