The hit family drama, SAITOU-SAN, which has become a sensation in Japan and internationally, returns again with a much awaited sequel after 5 years since the first series. The story of MASAKO SAITOU (Alisa Mizuki) and her son, Junichi, now a fourth grader, picks up from where the two move to Ootaka City. But on moving into the city, Saitou's reputation is tarnished by a bad rumor: she was known at her former kindergarten as a problematic parent who picked fights and had a knack of destroying harmony. On the other hand, MAYA YAMAUCHI (Mirei Kiritani) is a young mother whose son is enrolled in the same class as Saitou's. Maya devotes her time to be accepted by other parents and sees merit in conforming to the crowd.

One day, when she is at the shopping mall, a group of high school kids who are making a scene in public space, bump into Maya's son, TAKUMI. The non-apologetic delinquents start grouping up around Takumi and Maya while surrounding adults just watch indifferently. But Saitou steps in. She reprimands the kids that they are to blame and demands an apology, but Maya is totally taken aback by Saitou's actions. Maya, who is afraid of rocking any boat, feels that it would be best for her to stay away from the controversial Saitou--until Takumi creates an issue in the class that becomes a matter of an urgent parent-teacher meeting...

Alisa Mizuki, who plays the gallant Saitou, is a popular actress among viewers of all ages. It should be noted that SAITOU-SAN 2 is Mizuki's 26th leading role in a TV drama for the 22nd consequent year. Her co-star, Mirei Kiritani, a promising fashion model and actress, plays the young mother who eventually learns the most important things from Saitou. SAITOU-SAN 2 is a drama that will take the viewer on an entertaining journey that has something grounded for everybody to relate to while encouraging, raising good laughs, and acting as an excellent handbook in parenting.