When young Akiko marries mystery author Masakazu Isshiki and moves in with him in Kamakura, her way of life becomes a constant source of amazement.
A simple stroll through the streets brings her into contact with supernatural creatures such as spirits, goblins, ghosts, and not-grim-at-all reapers.
As Akiko learns very quickly, Kamakura is a place where humans and non-humans live side-by-side in harmony.

The Isshiki residence is also home to a parade of other distinctive denizens, such as Kin, a maid who may actually be 130 years old; Masakazu's incorrigible editor, Honda; and even a poverty-attracting entity.
Although Akiko's newlywed lifestyle isn't quite as she'd imagined, it still turns out to be a lot of hectic fun.

One morning, Masakazu awakes to find that Akiko has disappeared.
The only trace of her is a loving letter to her husband...
It seems that Akiko has met an unfortunate accident, died, and departed for the netherworld.
Upon losing his wife, Masakazu realizes for the first time how much he loves her. To bring Akiko back to life, he decides to journey to the netherworld himself.
What awaits Masakazu there are the supernatural creatures who took away his wife, and someone else he recognizes...
At last, the destiny of the desperate Isshikis will reveal itself.

DESTINY＝命运的意思是？

年轻的妻子亜紀子（高畑充希）嫁给了在鎌倉生活的推理小说家・一色正和（堺雅人）之后，遇到了很多神奇的事。
在路上走着就可以遇到魔鬼幽灵妖怪或者神仙，就连死神（安藤サクラ）也会出现。
原来鎌倉这里，是一个人和妖魔鬼怪可以友好共生的地方。

丈夫・正和除了写小说这个正业之外，还协助鎌倉警察署搜查办案，
再加上平时喜欢收集铁道模型，喜欢热带鱼等众多爱好，非常的忙碌。
这样的一色家里居然有实际年龄130歳? 的保姆・Kin（中村玉緒）、
还有穷神（田中泯）同住等等，他和责任编辑・本田（堤真一）是君子之交，
和个性丰富的人们热热闹闹过着每一天。
这虽和亜紀子的期待有点不大一样，但她还是开始了快乐的新婚生活。

但是、正和对亜紀子却隐瞒了一个秘密。
就是因为这个秘密，让正和一直以来对婚姻产生了很多疑虑。
可正和为什么会对亜紀子一见倾心呢？

有一天，病倒了的正和醒来后，却发现亜紀子的身影消失了。
她给丈夫留下了爱意满满的信――――
原来亜紀子遇到了意外事故去世了，走上了黄泉之路。
正和在失去之后才发现了自己对妻子・亜紀子的爱，为了挽救妻子的性命，决意一个人向黄泉出发。
在那里等待他的是把亜紀子带到黄泉的魔鬼们以及那个人・・・
一色夫妻的命运赌上了性命，从现在开始行动。